WHAT ARE THE CAUSES OF NEUROFIBROMATOSIS?

Neurofibromatosis is  caused by a misprint in the gene that is passed from a parent to a child. This is called autosomal dominant inheritance. Nf1 is more common on chromosome 17, they call it peripheral neurofibromatosis. NF2 is more common on chromosome 22, they call it central neurofibromatosis. They call it central because the effects are not usually seen from the outside of the body. All you need is one defective gene to have the disease. The chance of passing NF to an offspring is 50%.